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Pragmatic trials are studies designed to provide information for the real-world practice of clinical. They are typically described as focusing on practical aspects of study design, including the recruitment and consent process, as well as adherence and the use routinely available equipment.
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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which utilized a variety of investigators and included participants from different geographic areas. This type of heterogeneity, which is vital for pragmatic trials to be valid and to reduce bias in the results, is also necessary. Too much heterogeneity, 프라그마틱 무료슬롯 슬롯 환수율 - xyzbookmarks.Com - however, can cause problems with the trial design.
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Pragmatic trials seek to replicate real-world situations and have the highest external validity. They are typically requested by practitioners and policymakers in order to guide their decisions. They also provide a useful method of determining the causality between the intervention and its effects. However, they should not be used to substitute for explanation trials.
The concept of pragmatism is controversial and there are doubts about whether pragmatic trials can replace explanatory tests or if they should be an alternative to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which validate a physiological or clinical hypothesis as well as pragmatic trials that inform policy and practice decisions. They also proposed a framework for pragmatic trials, dubbed PRECIS.2 This tool attempted to define the elements of a pragmatic study which includes recruitment, design and 프라그마틱 슬롯 사이트 delivery of the intervention, as well as follow-up.
There is an encouraging increase in the number of pragmatic trials that are published. A recent Medline search using the keywords pragmatic and naturalistic, restricted to controlled trials randomized to control (RCTs) produced 34 articles, shown in red in Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatic thinking. However, it is important to note that the majority of these trials were conducted in primary care settings.